Catalog_noAB3073
Product_namePCGF6 Antibody (C-term)
Category抗原抗体
ReactivityH
Size100μL/50μL
Price2000.00/1100.00
immunogenHUMAN
SpecificityThis PCGF6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 261-295 amino acids from the C-terminal region of human PCGF6.
DilutionIF,1:25;WB,1:1000;
othernamePolycomb group RING finger protein 6, Mel18 and Bmi1-like RING finger, RING finger protein 134, PCGF6, MBLR, RNF134
IsotypeRabbit Ig
Background Transcriptional repressor. May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
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