Catalog_no | AB3083 |
Product_name | WDR5 Antibody (C-term) |
Category | 抗原抗体 |
Reactivity | H, M |
Size | 100μL/50μL |
Price | 2000.00/1100.00 |
immunogen | HUMAN |
Specificity | This WDR5 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 321-354 amino acids from the C-terminal region of human WDR5. |
Dilution | WB,1:1000; |
othername | WD repeat-containing protein 5, BMP2-induced 3-kb gene protein, WDR5, BIG3 |
Isotype | Rabbit Ig |
Background | Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation. |
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