| Catalog_no | AB3106 |
| Product_name | (Mouse) Smad2 Antibody (Center) |
| Category | 抗原抗体 |
| Reactivity | H, M, Rat |
| Size | 100μL/50μL |
| Price | 2000.00/1100.00 |
| immunogen | HUMAN |
| Specificity | This mouse Smad2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 198-232 amino acids from the Central region of mouse Smad2. |
| Dilution | WB,1:500-1:1000; |
| othername | Mothers against decapentaplegic homolog 2, MAD homolog 2, Mothers against DPP homolog 2, Mad-related protein 2, mMad2, SMAD family member 2, SMAD 2, Smad2, Smad2, Madh2, Madr2 |
| Isotype | Rabbit Ig |
| Background | Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator (By similarity). |
| Instructions | 
查看与下载 |
| Share |
