Catalog_noAB3160
Product_name(DANRE) sh3bp4a Antibody (N-term)
Category抗原抗体
ReactivityZf
Size100μL/50μL
Price2000.00/1100.00
immunogenHUMAN
SpecificityThis DANRE sh3bp4a antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 132-165 amino acids from the N-terminal region of DANRE sh3bp4a.
DilutionWB,1:1000;
othernameSH3 domain-binding protein 4-A, sh3bp4a, sh3bp4
IsotypeRabbit Ig
Background Possible role in regulating endocytosis of the transferrin receptor at the plasma membrane. Alternatively, may function as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes. Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation. Thereby, may indirectly regulate cell growth, proliferation and autophagy (By similarity).
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