Catalog_noAB3162
Product_namePTGDS Antibody (C-term)
Category抗原抗体
ReactivityM
Size100μL/50μL
Price2000.00/1100.00
immunogenHUMAN
SpecificityThis PTGDS antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 149-182 amino acids from the C-terminal region of human PTGDS.
DilutionWB,1:1000;
othernameProstaglandin-H2 D-isomerase, Beta-trace protein, Cerebrin-28, Glutathione-independent PGD synthase, Lipocalin-type prostaglandin-D synthase, Prostaglandin-D2 synthase, PGD2 synthase, PGDS, PGDS2, PTGDS, PDS
IsotypeRabbit Ig
Background Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system.
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