| Catalog_no | AB3314 |
| Product_name | (Mouse) Hopx Antibody (Center) |
| Category | 抗原抗体 |
| Reactivity | H, M, Rat |
| Size | 100μL/50μL |
| Price | 2000.00/1100.00 |
| immunogen | HUMAN |
| Specificity | This Mouse Hopx antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 22-54 amino acids from the Central region of Mouse Hopx. |
| Dilution | WB,1:1000; |
| othername | Homeodomain-only protein, Homeobox-only protein, Odd homeobox protein 1, mOB1, Hopx, Hod, Hop, Ob1 |
| Isotype | Rabbit Ig |
| Background | Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy. |
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