Catalog_noAB3321
Product_nameSUZ12 Antibody (Center)
Category抗原抗体
ReactivityH, M
Size100μL/50μL
Price2000.00/1100.00
immunogenHUMAN
SpecificityThis SUZ12 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 375-408 amino acids from the Central region of human SUZ12.
DilutionWB,1:2000;
othernamePolycomb protein SUZ12, Chromatin precipitated E2F target 9 protein, ChET 9 protein, Joined to JAZF1 protein, Suppressor of zeste 12 protein homolog, SUZ12, CHET9, JJAZ1, KIAA0160
IsotypeRabbit Ig
Background Polycomb group (PcG) protein. Component of the PRC2/EED- EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.
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