| Catalog_no | AB3343 |
| Product_name | (Mouse) Bmi1 Antibody (Center) |
| Category | 抗原抗体 |
| Reactivity | M |
| Size | 100μL/50μL |
| Price | 2000.00/1100.00 |
| immunogen | HUMAN |
| Specificity | This Mouse Bmi1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 109-143 amino acids from the Central region of Mouse Bmi1. |
| Dilution | WB,1:2000;WB,1:2000; |
| othername | Polycomb complex protein BMI-1, Polycomb group RING finger protein 4, Bmi1, Bmi-1, Pcgf4 |
| Isotype | Rabbit Ig |
| Background | Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2 (By similarity). |
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