Catalog_noAB3401
Product_name(DANRE) srrt Antibody (C-Term)
Category抗原抗体
ReactivityH, Zf
Size100μL/50μL
Price2000.00/1100.00
immunogenHUMAN
SpecificityThis DANRE srrt antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 733-766 amino acids from DANRE srrt.
DilutionWB,1:2000;
othernameSerrate RNA effector molecule homolog, Arsenite-resistance protein 2, srrt, ars2
IsotypeRabbit Ig
Background Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs (By similarity). Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self- renewal. Does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity).
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