Catalog_noAB3412
Product_name(DANRE) tie2 Antibody (N-term)
Category抗原抗体
ReactivityZf
Size100μL/50μL
Price2000.00/1100.00
immunogenHUMAN
SpecificityThis (DANRE) tie2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 160-194 amino acids from the N-terminal region of DANRE tie2.
DilutionWB,1:2000;
othernameTyrosine-protein kinase receptor Tie-2, Tyrosine kinase with Ig and EGF homology domains-2, tie2, tie-2
IsotypeRabbit Ig
Background Tyrosine-protein kinase that acts as cell-surface receptor for angiopoietins and regulates angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Can activate or inhibit angiogenesis, depending on the context. Angiopoietin signaling triggers receptor dimerization and autophosphorylation at specific tyrosine residues that then serve as binding sites for scaffold proteins and effectors (By similarity).
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