Catalog_noAB3471
Product_nameDENR Antibody
Category抗原抗体
ReactivityH
Size100μL/50μL
Price2000.00/1100.00
immunogenHUMAN
SpecificityThis DENR antibody is generated from a mouse immunized with a recombinant protein of human DENR.
DilutionIF,1:25;FC,1:25;IHC-P,1:25;WB,1:1000-1:2000;
othernameDensity-regulated protein, DRP, Protein DRP1, Smooth muscle cell-associated protein 3, SMAP-3, DENR, DRP1
IsotypeIgG2b,κ
Background May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1.
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