Catalog_noAB3526
Product_nameATP5E Antibody (C-Term)
Category抗原抗体
ReactivityH
Size100μL/50μL
Price2000.00/1100.00
immunogenHUMAN
SpecificityThis ATP5E antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 21-51 amino acids from human ATP5E.
DilutionWB,1:2000;
othernameATP synthase subunit epsilon, mitochondrial, ATPase subunit epsilon, ATP5E
IsotypeRabbit Ig
Background Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits (By similarity).
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