Catalog_no | AB3677 |
Product_name | PACSIN2 Antibody |
Category | 抗原抗体 |
Reactivity | H, M |
Size | 100μL/50μL |
Price | 2000.00/1100.00 |
immunogen | HUMAN |
Specificity | This PACSIN2 antibody is generated from a mouse immunized with a recombinant protein between 250-486 amino acids from human PACSIN2. |
Dilution | WB,1:2000; |
othername | Protein kinase C and casein kinase substrate in neurons protein 2, Syndapin-2, Syndapin-II, PACSIN2 |
Isotype | IgG1,k |
Background | Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle- mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. May also play a role in the formation of caveolae at the cell membrane. Recruits DNM2 to caveolae, and thereby plays a role in caveola-mediated endocytosis. |
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