Catalog_no | AB3711 |
Product_name | IL23A Antibody (Center) |
Category | 抗原抗体 |
Reactivity | H, M |
Size | 100μL/50μL |
Price | 2000.00/1100.00 |
immunogen | HUMAN |
Specificity | This IL23A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 33-67 amino acids from the Central region of human IL23A. |
Dilution | FC,1:25;WB,1:2000; |
othername | Interleukin-23 subunit alpha, IL-23 subunit alpha, IL-23-A, Interleukin-23 subunit p19, IL-23p19, IL23A, SGRF |
Isotype | Rabbit Ig |
Background | Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak- Stat signaling cascade, stimulates memory rather than naive T- cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. |
Instructions |
查看与下载 |
Share |
|