Catalog_noAN3161
Product_nameK2C6B rabbit pAb
Category抗原抗体
ApplicationsWB
ReactivityHuman, Mouse
Size100μg/50μg/20μg
Price2000.00/1100.00/500.00
Gene_nameKRT6B K6B KRTL1
Protein_nameK2C6B
Human swiss prot no3854
Human swiss prot noP04259
Mouse gene id0
Mouse swiss prot noQ9Z331
immunogenSynthesized peptide derived from human K2C6B
SpecificityThis antibody detects endogenous levels of K2C6B at Human/Mouse
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.119% sodium azide.
SourceRabbit
DilutionWB 1:500-2000
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage_stability-20°C/1 year
othernameKeratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK-6B) (Keratin-6B) (K6B) (Type-II keratin Kb10)
Observed_band60KD
BackgroundThe protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008],
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