| Catalog_no | AN3174 |
| Product_name | FBXW5 rabbit pAb |
| Category | 抗原抗体 |
| Applications | WB |
| Reactivity | Human, Mouse,Rat |
| Size | 100μg/50μg/20μg |
| Price | 2000.00/1100.00/500.00 |
| Gene_name | FBXW5 FBW5 PP3971 |
| Protein_name | FBXW5 |
| Human swiss prot no | 54461 |
| Human swiss prot no | Q969U6 |
| Mouse gene id | 30839 |
| Mouse swiss prot no | Q9QXW2 |
| Rat gene id | 362081 |
| Rat swiss prot no | Q4KLI9 |
| immunogen | Synthesized peptide derived from human FBXW5 |
| Specificity | This antibody detects endogenous levels of FBXW5 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.132% sodium azide. |
| Source | Rabbit |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage_stability | -20°C/1 year |
| othername | F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5) |
| Observed_band | 60KD |
| Background | This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains WD-40 domains, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, however, they were found to be nonsense-mediated mRNA decay (NMD) candidates, hence not represented. [provided by RefSeq, Jul 2008], |
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