| Catalog_no | AN3266 |
| Product_name | NOD1 rabbit pAb |
| Category | 抗原抗体 |
| Applications | WB |
| Reactivity | Human, Mouse |
| Size | 100μg/50μg/20μg |
| Price | 2000.00/1100.00/500.00 |
| Gene_name | NOD1 CARD4 |
| Protein_name | NOD1 |
| Human swiss prot no | 10392 |
| Human swiss prot no | Q9Y239 |
| Mouse gene id | 107607 |
| Mouse swiss prot no | Q8BHB0 |
| immunogen | Synthesized peptide derived from human NOD1 |
| Specificity | This antibody detects endogenous levels of NOD1 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.224% sodium azide. |
| Source | Rabbit |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage_stability | -20°C/1 year |
| othername | Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4) |
| Observed_band | 105KD |
| Background | This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Oct 2009], |
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