| Catalog_no | AN3291 |
| Product_name | DSE rabbit pAb |
| Category | 抗原抗体 |
| Applications | WB |
| Reactivity | Human, Mouse |
| Size | 100μg/50μg/20μg |
| Price | 2000.00/1100.00/500.00 |
| Gene_name | DSE SART2 |
| Protein_name | DSE |
| Human swiss prot no | 29940 |
| Human swiss prot no | Q9UL01 |
| Mouse gene id | 212898 |
| Mouse swiss prot no | Q8BLI4 |
| immunogen | Synthesized peptide derived from human DSE |
| Specificity | This antibody detects endogenous levels of DSE at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.249% sodium azide. |
| Source | Rabbit |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage_stability | -20°C/1 year |
| othername | Dermatan-sulfate epimerase (DS epimerase) (EC 5.1.3.19) (Chondroitin-glucuronate 5-epimerase) (Squamous cell carcinoma antigen recognized by T-cells 2) (SART-2) |
| Observed_band | 105KD |
| Background | The protein encoded by this gene is a tumor-rejection antigen. It is localized to the endoplasmic reticulum and functions to convert D-glucuronic acid to L-iduronic acid during the biosynthesis of dermatan sulfate. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. Mutations in this gene cause inmusculocontractural Ehlers-Danlos syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 9, and a paralogous gene exists on chromosome 18. [provided by RefSeq, Apr 2016], |
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