| Catalog_no | AN3298 |
| Product_name | FGD1 rabbit pAb |
| Category | 抗原抗体 |
| Applications | WB |
| Reactivity | Human, Mouse |
| Size | 100μg/50μg/20μg |
| Price | 2000.00/1100.00/500.00 |
| Gene_name | FGD1 FGDY ZFYVE3 |
| Protein_name | FGD1 |
| Human swiss prot no | 2245 |
| Human swiss prot no | P98174 |
| Mouse gene id | 14163 |
| Mouse swiss prot no | P52734 |
| immunogen | Synthesized peptide derived from human FGD1 |
| Specificity | This antibody detects endogenous levels of FGD1 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.256% sodium azide. |
| Source | Rabbit |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage_stability | -20°C/1 year |
| othername | FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF) (Zinc finger FYVE domain-containing protein 3) |
| Observed_band | 105KD |
| Background | This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of faciogenital dysplasia and X-linked mental retardation, syndromatic 16.[provided by RefSeq, Mar 2011], |
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