Catalog_no | AN3319 |
Product_name | SNX13 rabbit pAb |
Category | 抗原抗体 |
Applications | WB |
Reactivity | Human, Mouse |
Size | 100μg/50μg/20μg |
Price | 2000.00/1100.00/500.00 |
Gene_name | SNX13 KIAA0713 |
Protein_name | SNX13 |
Human swiss prot no | 23161 |
Human swiss prot no | Q9Y5W8 |
Mouse gene id | 217463 |
Mouse swiss prot no | Q6PHS6 |
immunogen | Synthesized peptide derived from human SNX13 |
Specificity | This antibody detects endogenous levels of SNX13 at Human/Mouse |
Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.277% sodium azide. |
Source | Rabbit |
Dilution | WB 1:500-2000 |
Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
Concentration | 1 mg/ml |
Storage_stability | -20°C/1 year |
othername | Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) |
Observed_band | 105KD |
Background | This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking. [provided by RefSeq, Jul 2008], |
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