Catalog_noAN3319
Product_nameSNX13 rabbit pAb
Category抗原抗体
ApplicationsWB
ReactivityHuman, Mouse
Size100μg/50μg/20μg
Price2000.00/1100.00/500.00
Gene_nameSNX13 KIAA0713
Protein_nameSNX13
Human swiss prot no23161
Human swiss prot noQ9Y5W8
Mouse gene id217463
Mouse swiss prot noQ6PHS6
immunogenSynthesized peptide derived from human SNX13
SpecificityThis antibody detects endogenous levels of SNX13 at Human/Mouse
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.277% sodium azide.
SourceRabbit
DilutionWB 1:500-2000
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage_stability-20°C/1 year
othernameSorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1)
Observed_band105KD
BackgroundThis gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking. [provided by RefSeq, Jul 2008],
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