| Catalog_no | AN3321 |
| Product_name | PCSK6 rabbit pAb |
| Category | 抗原抗体 |
| Applications | WB |
| Reactivity | Human,Rat |
| Size | 100μg/50μg/20μg |
| Price | 2000.00/1100.00/500.00 |
| Gene_name | PCSK6 PACE4 |
| Protein_name | PCSK6 |
| Human swiss prot no | 5046 |
| Human swiss prot no | P29122 |
| Rat gene id | 25507 |
| Rat swiss prot no | Q63415 |
| immunogen | Synthesized peptide derived from human PCSK6 |
| Specificity | This antibody detects endogenous levels of PCSK6 at Human/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.279% sodium azide. |
| Source | Rabbit |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage_stability | -20°C/1 year |
| othername | Proprotein convertase subtilisin/kexin type 6 (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin-like proprotein convertase 4) (SPC4) (Subtilisin/kexin-like protease PACE4) |
| Observed_band | 105KD |
| Background | This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the trans-Golgi network where a second autocatalytic event takes place and the catalytic activity is acquired. The encoded protease is constitutively secreted into the extracellular matrix and expressed in many tissues, including neuroendocrine, liver, gut, and brain. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. Some of its substrates include transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression and left-right patterning. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Feb 2014], |
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