Catalog_noAN3358
Product_nameSIM1 rabbit pAb
Category抗原抗体
ApplicationsWB
ReactivityHuman, Mouse
Size100μg/50μg/20μg
Price2000.00/1100.00/500.00
Gene_nameSIM1 BHLHE14
Protein_nameSIM1
Human swiss prot no6492
Human swiss prot noP81133
Mouse gene id20464
Mouse swiss prot noQ61045
immunogenSynthesized peptide derived from human SIM1
SpecificityThis antibody detects endogenous levels of SIM1 at Human/Mouse
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.316% sodium azide.
SourceRabbit
DilutionWB 1:500-2000
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage_stability-20°C/1 year
othernameSingle-minded homolog 1 (Class E basic helix-loop-helix protein 14) (bHLHe14)
Observed_band85KD
BackgroundSIM1 and SIM2 genes are Drosophila single-minded (sim) gene homologs. SIM1 transcript was detected only in fetal kidney out of various adult and fetal tissues tested. Since the sim gene plays an important role in Drosophila development and has peak levels of expression during the period of neurogenesis,it was proposed that the human SIM gene is a candidate for involvement in certain dysmorphic features (particularly the facial and skull characteristics), abnormalities of brain development, and/or mental retardation of Down syndrome. [provided by RefSeq, Jul 2008],
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