Catalog_noAN3545
Product_nameNUDT5 rabbit pAb
Category抗原抗体
ApplicationsWB
ReactivityHuman, Mouse,Rat
Size100μg/50μg/20μg
Price2000.00/1100.00/500.00
Gene_nameNUDT5 HSPC115
Protein_nameNUDT5
Human swiss prot no11164
Human swiss prot noQ9UKK9
Mouse gene id53893
Mouse swiss prot noQ9JKX6
Rat gene id361274
Rat swiss prot noQ6AY63
immunogenSynthesized peptide derived from human NUDT5
SpecificityThis antibody detects endogenous levels of NUDT5 at Human/Mouse/Rat
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
SourceRabbit
DilutionWB 1:500-2000
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage_stability-20°C/1 year
BackgroundThis gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates, including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues, resulting in the inhibition of ATP-activated potassium channels. 8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA. Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors. [provided by RefSeq, Aug 2013],
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