Catalog_noAN3665
Product_nameTNNC1 rabbit pAb
Category抗原抗体
ApplicationsWB
ReactivityHuman, Mouse
Size100μg/50μg/20μg
Price2000.00/1100.00/500.00
Gene_nameTNNC1 TNNC
Protein_nameTNNC1
Human swiss prot no7134
Human swiss prot noP63316
Mouse gene id21924
Mouse swiss prot noP19123
immunogenSynthesized peptide derived from human TNNC1
SpecificityThis antibody detects endogenous levels of TNNC1 at Human/Mouse
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
SourceRabbit
DilutionWB 1:500-2000
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage_stability-20°C/1 year
BackgroundTroponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z. [provided by RefSeq, Oct 2008],
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