Catalog_no | AN3838 |
Product_name | DSC1 rabbit pAb |
Category | 抗原抗体 |
Applications | WB |
Reactivity | Human, Mouse |
Size | 100μg/50μg/20μg |
Price | 2000.00/1100.00/500.00 |
Gene_name | DSC1 CDHF1 |
Protein_name | DSC1 |
Human swiss prot no | 1823 |
Human swiss prot no | Q08554 |
Mouse gene id | |
Mouse swiss prot no | P55849 |
immunogen | Synthesized peptide derived from human DSC1 |
Specificity | This antibody detects endogenous levels of DSC1 at Human/Mouse |
Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Source | Rabbit |
Dilution | WB 1:500-2000 |
Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
Concentration | 1 mg/ml |
Storage_stability | -20°C/1 year |
Background | The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. A subtype of IgA pemphigus, a life-threatening autoimmune disease, is characterized by the presence of autoantibodies that target the encoded protein. The desmosomal family members are arranged in two clusters on chromosome 18. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protein. [provided by RefSeq, Nov 2015], |
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