Catalog_noAN3898
Product_nameAT2B4 rabbit pAb
Category抗原抗体
ApplicationsWB
ReactivityHuman,Rat
Size100μg/50μg/20μg
Price2000.00/1100.00/500.00
Gene_nameATP2B4 ATP2B2 MXRA1
Protein_nameAT2B4
Human swiss prot no493
Human swiss prot noP23634
Rat gene id29600
Rat swiss prot noQ64542
immunogenSynthesized peptide derived from human AT2B4
SpecificityThis antibody detects endogenous levels of AT2B4 at Human/Rat
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
SourceRabbit
DilutionWB 1:500-2000
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage_stability-20°C/1 year
BackgroundThe protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 4. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
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