Catalog_no | AN4007 |
Product_name | GEN rabbit pAb |
Category | 抗原抗体 |
Applications | WB |
Reactivity | Human, Mouse |
Size | 100μg/50μg/20μg |
Price | 2000.00/1100.00/500.00 |
Gene_name | GEN1 |
Protein_name | GEN |
Human swiss prot no | 348654 |
Human swiss prot no | Q17RS7 |
Mouse gene id | 209334 |
Mouse swiss prot no | Q8BMI4 |
immunogen | Synthesized peptide derived from human GEN |
Specificity | This antibody detects endogenous levels of GEN at Human/Mouse |
Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Source | Rabbit |
Dilution | WB 1:500-2000 |
Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
Concentration | 1 mg/ml |
Storage_stability | -20°C/1 year |
Background | This gene encodes a member of the Rad2/xeroderma pigmentosum group G nuclease family, whose members are characterized by N-terminal and internal xeroderma pigmentosum group G nuclease domains followed by helix-hairpin-helix domains and disordered C-terminal domains. The protein encoded by this gene is involved in resolution of Holliday junctions, which are intermediate four-way structures that covalently link DNA during homologous recombination and double-strand break repair. The protein resolves Holliday junctions by creating dual incisions across the junction to produce nicked duplex products that can be ligated. In addition, this protein has been found to localize to centrosomes where it has been implicated in regulation of centrosome integrity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016], |
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