Catalog_noAN4130
Product_nameSSX2 rabbit pAb
Category抗原抗体
ApplicationsWB
ReactivityHuman
Size100μg/50μg/20μg
Price2000.00/1100.00/500.00
Gene_nameSSX2 SSX2A; SSX2B
Protein_nameSSX2
Human swiss prot no6757
Human swiss prot noQ16385
immunogenSynthesized peptide derived from human SSX2
SpecificityThis antibody detects endogenous levels of SSX2 at Human
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
SourceRabbit
DilutionWB 1:500-2000
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage_stability-20°C/1 year
BackgroundThe product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX1 and SSX4 family members, have been involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. This gene also has an identical duplicate, GeneID: 727837, located about 45 kb downstream in the opposite orientation on chromosome X. [provided by RefSeq, Jul 2013],
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