Catalog_noAN4211
Product_nameSIAH1 rabbit pAb
Category抗原抗体
ApplicationsWB
ReactivityHuman,Rat
Size100μg/50μg/20μg
Price2000.00/1100.00/500.00
Gene_nameSIAH1 HUMSIAH
Protein_nameSIAH1
Human swiss prot no6477
Human swiss prot noQ8IUQ4
Rat gene id140941
Rat swiss prot noQ920M9
immunogenSynthesized peptide derived from human SIAH1
SpecificityThis antibody detects endogenous levels of SIAH1 at Human/Rat
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
SourceRabbit
DilutionWB 1:500-2000
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage_stability-20°C/1 year
Backgroundsiah E3 ubiquitin protein ligase 1(SIAH1) Homo sapiens This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008],
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