| Catalog_no | AT6683 |
| Product_name | S12A3 rabbit pAb |
| Category | 抗原抗体 |
| Applications | WB |
| Reactivity | Human, Mouse,Rat |
| Size | 100μg/50μg/20μg |
| Price | 2000.00/1100.00/500.00 |
| Gene_name | SLC12A3 TSC |
| Protein_name | S12A3 |
| Human swiss prot no | 6559 |
| Human swiss prot no | P55017 |
| Mouse gene id | 20497 |
| Mouse swiss prot no | P59158 |
| Rat gene id | 54300 |
| Rat swiss prot no | P55018 |
| immunogen | Synthesized peptide derived from human S12A3 |
| Specificity | This antibody detects endogenous levels of S12A3 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | Rabbit |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage_stability | -20°C/1 year |
| Background | This gene encodes a renal thiazide-sensitive sodium-chloride cotransporter that is important for electrolyte homeostasis. This cotransporter mediates sodium and chloride reabsorption in the distal convoluted tubule. Mutations in this gene cause Gitelman syndrome, a disease similar to Bartter's syndrome, that is characterized by hypokalemic alkalosis combined with hypomagnesemia, low urinary calcium, and increased renin activity associated with normal blood pressure. This cotransporter is the target for thiazide diuretics that are used for treating high blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
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