Catalog_noAT6728
Product_nameAL7A1 rabbit pAb
Category抗原抗体
ApplicationsWB
ReactivityHuman, Mouse,Rat
Size100μg/50μg/20μg
Price2000.00/1100.00/500.00
Gene_nameALDH7A1 ATQ1
Protein_nameAL7A1
Human swiss prot no501
Human swiss prot noP49419
Mouse gene id110695
Mouse swiss prot noQ9DBF1
Rat gene id291450
Rat swiss prot noQ64057
immunogenSynthesized peptide derived from human AL7A1
SpecificityThis antibody detects endogenous levels of AL7A1 at Human/Mouse/Rat
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
SourceRabbit
DilutionWB 1:500-2000
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage_stability-20°C/1 year
BackgroundThe protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified. [provided by RefSeq, Jan 2011],
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