| Catalog_no | AT6883 |
| Product_name | DUOX1 rabbit pAb |
| Category | 抗原抗体 |
| Applications | WB |
| Reactivity | Human,Rat |
| Size | 100μg/50μg/20μg |
| Price | 2000.00/1100.00/500.00 |
| Gene_name | DUOX1 DUOX LNOX1 THOX1 |
| Protein_name | DUOX1 |
| Human swiss prot no | 53905 |
| Human swiss prot no | Q9NRD9 |
| Rat gene id | 266807 |
| Rat swiss prot no | Q8CIY2 |
| immunogen | Synthesized peptide derived from human DUOX1 |
| Specificity | This antibody detects endogenous levels of DUOX1 at Human/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | Rabbit |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage_stability | -20°C/1 year |
| Background | The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase, lactoperoxidase, and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2012], |
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