Catalog_no | AT6896 |
Product_name | UBA3 rabbit pAb |
Category | 抗原抗体 |
Applications | WB |
Reactivity | Human, Mouse,Rat |
Size | 100μg/50μg/20μg |
Price | 2000.00/1100.00/500.00 |
Gene_name | UBA3 UBE1C |
Protein_name | UBA3 |
Human swiss prot no | 9039 |
Human swiss prot no | Q8TBC4 |
Mouse gene id | 22200 |
Mouse swiss prot no | Q8C878 |
Rat gene id | 117553 |
Rat swiss prot no | Q99MI7 |
immunogen | Synthesized peptide derived from human UBA3 |
Specificity | This antibody detects endogenous levels of UBA3 at Human/Mouse/Rat |
Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Source | Rabbit |
Dilution | WB 1:500-2000 |
Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
Concentration | 1 mg/ml |
Storage_stability | -20°C/1 year |
Background | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
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