Catalog_no | AT6919 |
Product_name | PDE11 rabbit pAb |
Category | 抗原抗体 |
Applications | WB |
Reactivity | Human, Mouse,Rat |
Size | 100μg/50μg/20μg |
Price | 2000.00/1100.00/500.00 |
Gene_name | PDE11A |
Protein_name | PDE11 |
Human swiss prot no | 50940 |
Human swiss prot no | Q9HCR9 |
Mouse gene id | 241489 |
Mouse swiss prot no | P0C1Q2 |
Rat gene id | 140928 |
Rat swiss prot no | Q8VID6 |
immunogen | Synthesized peptide derived from human PDE11 |
Specificity | This antibody detects endogenous levels of PDE11 at Human/Mouse/Rat |
Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Source | Rabbit |
Dilution | WB 1:500-2000 |
Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
Concentration | 1 mg/ml |
Storage_stability | -20°C/1 year |
Background | The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
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