Catalog_noAT7171
Product_nameDYL1 rabbit pAb
Category抗原抗体
ApplicationsIHC-p
ReactivityHuman, Mouse,Rat
Size100μg/50μg/20μg
Price2000.00/1100.00/500.00
Gene_nameDYNLL1 DLC1 DNCL1 DNCLC1 HDLC1
Protein_nameDYL1
Human swiss prot no8655
Human swiss prot noP63167
Mouse gene id56455
Mouse swiss prot noP63168
Rat gene id58945
Rat swiss prot noP63170
immunogenSynthesized peptide derived from human DYL1
SpecificityThis antibody detects endogenous levels of DYL1 at Human/Mouse/Rat
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
SourceRabbit
DilutionIHC-p 1:50-200
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage_stability-20°C/1 year
BackgroundCytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008],
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