| Catalog_no | AT7297 |
| Product_name | NPC1 rabbit pAb |
| Category | 抗原抗体 |
| Applications | WB |
| Reactivity | Human, Mouse |
| Size | 100μg/50μg/20μg |
| Price | 2000.00/1100.00/500.00 |
| Gene_name | NPC1 |
| Protein_name | NPC1 |
| Human swiss prot no | 4864 |
| Human swiss prot no | O15118 |
| Mouse gene id | |
| Mouse swiss prot no | O35604 |
| immunogen | Synthesized peptide derived from human NPC1 |
| Specificity | This antibody detects endogenous levels of NPC1 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | Rabbit |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage_stability | -20°C/1 year |
| Background | This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pick type C disease, a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments.[provided by RefSeq, Aug 2009], |
| Instructions | 
查看与下载 |
| Share |
Copyright © 2021 苏州博特龙免疫技术有限公司 版权所有 ，苏ICP备2021013855号-1
苏公网安备32050702011981号 
