Catalog_noAT7479
Product_nameFBX18 rabbit pAb
Category抗原抗体
ApplicationsWB
ReactivityHuman, Mouse
Size100μg/50μg/20μg
Price2000.00/1100.00/500.00
Gene_nameFBXO18 FBH1 FBX18
Protein_nameFBX18
Human swiss prot no84893
Human swiss prot noQ8NFZ0
Mouse gene id50755
Mouse swiss prot noQ8K2I9
immunogenSynthesized peptide derived from human FBX18
SpecificityThis antibody detects endogenous levels of FBX18 at Human/Mouse
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
SourceRabbit
DilutionWB 1:500-2000
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage_stability-20°C/1 year
BackgroundThis gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. It contains an F-box motif and seven conserved helicase motifs, and has both DNA-dependent ATPase and DNA unwinding activities. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],
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