| Catalog_no | AP1272 |
| Product_name | BAP1 (phospho-Ser592) rabbit pAb |
| Category | 抗原抗体 |
| Applications | WB |
| Reactivity | Human |
| Size | 100μg/50μg/20μg |
| Price | 2200.00/1200.00/560.00 |
| Gene_name | BAP1 KIAA0272 hucep-6 |
| Protein_name | BAP1 (Ser592) |
| Human swiss prot no | 8314 |
| Human swiss prot no | Q92560 |
| Mouse gene id | 104416 |
| Mouse swiss prot no | Q99PU7 |
| Rat gene id | 306257 |
| Rat swiss prot no | D3ZHS6 |
| immunogen | Synthesized phosho peptide around human BAP1 (Ser592) |
| Specificity | This antibody detects endogenous levels of Human BAP1 (phospho-Ser592) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | Rabbit |
| Dilution | WB 1:1000-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage_stability | -20°C/1 year |
| othername | Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1-associated protein 1) (Cerebral protein 6) |
| Observed_band | 80KD |
| Background | BRCA1 associated protein 1(BAP1) Homo sapiens This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma. [provided by RefSeq, May 2013], |
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