| Catalog_no | AP1285 |
| Product_name | CaMKK2 (phospho-Ser511) rabbit pAb |
| Category | 抗原抗体 |
| Applications | WB |
| Reactivity | Human,Mouse,Rat |
| Size | 100μg/50μg/20μg |
| Price | 2200.00/1200.00/560.00 |
| Gene_name | CAMKK2 CAMKKB KIAA0787 |
| Protein_name | CaMKK2 (Ser511) |
| Human swiss prot no | 10645 |
| Human swiss prot no | Q96RR4 |
| Mouse gene id | 207565 |
| Mouse swiss prot no | Q8C078 |
| Rat gene id | 83506 |
| Rat swiss prot no | O88831 |
| immunogen | Synthesized phosho peptide around human CaMKK2 (Ser511) |
| Specificity | This antibody detects endogenous levels of Human Mouse Rat CaMKK2 (phospho-Ser511) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | Rabbit |
| Dilution | WB 1:1000-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage_stability | -20°C/1 year |
| othername | Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) (CaMKK 2) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-KK beta) (CaM-kinase kinase beta) (CaMKK beta) |
| Observed_band | 65KD |
| Background | calcium/calmodulin dependent protein kinase kinase 2(CAMKK2) Homo sapiens The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases. [provided by RefSeq, Jul 2012], |
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