| Catalog_no | AP1286 |
| Product_name | CARD11 (phospho-Ser652) rabbit pAb |
| Category | 抗原抗体 |
| Applications | WB |
| Reactivity | Human,Mouse,Rat |
| Size | 100μg/50μg/20μg |
| Price | 2200.00/1200.00/560.00 |
| Gene_name | CARD11 CARMA1 |
| Protein_name | CARD11 (Ser652) |
| Human swiss prot no | 84433 |
| Human swiss prot no | Q9BXL7 |
| Mouse gene id | 108723 |
| Mouse swiss prot no | Q8CIS0 |
| immunogen | Synthesized phosho peptide around human CARD11 (Ser652) |
| Specificity | This antibody detects endogenous levels of Human Mouse Rat CARD11 (phospho-Ser652) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | Rabbit |
| Dilution | WB 1:1000-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage_stability | -20°C/1 year |
| othername | Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 1) (Carma 1) |
| Observed_band | 130KD |
| Background | caspase recruitment domain family member 11(CARD11) Homo sapiens The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008], |
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