| Catalog_no | AP1328 |
| Product_name | eIF4G (phospho-Ser1108) rabbit pAb |
| Category | 抗原抗体 |
| Applications | WB |
| Reactivity | Human,Mouse,Rat |
| Size | 100μg/50μg/20μg |
| Price | 2200.00/1200.00/560.00 |
| Gene_name | EIF4G1 EIF4F EIF4G EIF4GI |
| Protein_name | eIF4G (Ser1108) |
| Human swiss prot no | 1981 |
| Human swiss prot no | Q04637 |
| Mouse gene id | 208643 |
| Mouse swiss prot no | Q6NZJ6 |
| immunogen | Synthesized phosho peptide around human eIF4G (Ser1108) |
| Specificity | This antibody detects endogenous levels of Human Mouse Rat eIF4G (phospho-Ser1108) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | Rabbit |
| Dilution | WB 1:1000-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage_stability | -20°C/1 year |
| othername | Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) (p220) |
| Observed_band | 180KD |
| Background | eukaryotic translation initiation factor 4 gamma 1(EIF4G1) Homo sapiens The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq, Aug 2010], |
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