Catalog_noAP1333
Product_nameFGF Receptor (phospho-Tyr653/654) rabbit pAb
Category抗原抗体
ApplicationsWB
ReactivityHuman
Size100μg/50μg/20μg
Price2200.00/1200.00/560.00
Gene_nameFGFR1 BFGFR CEK FGFBR FLG FLT2 HBGFR
Protein_nameFGF Receptor (Tyr653/654)
Human swiss prot no2260
Human swiss prot noP11362
Mouse gene id14182
Mouse swiss prot noP16092
Rat gene id79114
Rat swiss prot noQ04589
immunogenSynthesized phosho peptide around human FGF Receptor (Tyr653 and 654)
SpecificityThis antibody detects endogenous levels of Human FGF Receptor (phospho-Tyr653 or 654)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
SourceRabbit
DilutionWB 1:1000-2000
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage_stability-20°C/1 year
othernameFibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
Observed_band120KD
Backgroundfibroblast growth factor receptor 1(FGFR1) Homo sapiens The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome,
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