| Catalog_no | AP1358 |
| Product_name | IGF-I Receptor β (phospho-Tyr1131) rabbit pAb |
| Category | 抗原抗体 |
| Applications | WB |
| Reactivity | Human |
| Size | 100μg/50μg/20μg |
| Price | 2200.00/1200.00/560.00 |
| Gene_name | IGF1R |
| Protein_name | IGF-I Receptor β (Tyr1131) |
| Human swiss prot no | 3480 |
| Human swiss prot no | P08069 |
| Mouse gene id | 16001 |
| Mouse swiss prot no | Q60751 |
| Rat gene id | 25718 |
| Rat swiss prot no | P24062 |
| immunogen | Synthesized phosho peptide around human IGF-I Receptor β (Tyr1131) |
| Specificity | This antibody detects endogenous levels of Human IGF-I Receptor β (phospho-Tyr1131) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | Rabbit |
| Dilution | WB 1:1000-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage_stability | -20°C/1 year |
| othername | Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] |
| Observed_band | 155KD |
| Background | insulin like growth factor 1 receptor(IGF1R) Homo sapiens This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014], |
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