| Catalog_no | AP1363 |
| Product_name | Insulin Receptor β (phospho-Tyr1345) rabbit pAb |
| Category | 抗原抗体 |
| Applications | WB |
| Reactivity | Human |
| Size | 100μg/50μg/20μg |
| Price | 2200.00/1200.00/560.00 |
| Gene_name | INSR |
| Protein_name | Insulin Receptor β (Tyr1345) |
| Human swiss prot no | 3643 |
| Human swiss prot no | P06213 |
| Mouse gene id | 16337 |
| Mouse swiss prot no | P15208 |
| Rat swiss prot no | P15127 |
| immunogen | Synthesized phosho peptide around human Insulin Receptor β (Tyr1345) |
| Specificity | This antibody detects endogenous levels of Human Insulin Receptor β (phospho-Tyr1345) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | Rabbit |
| Dilution | WB 1:1000-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage_stability | -20°C/1 year |
| othername | Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta] |
| Observed_band | 95KD |
| Background | insulin receptor(INSR) Homo sapiens This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015], |
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