| Catalog_no | AP1387 |
| Product_name | LRP6 (phospho-Ser1490) rabbit pAb |
| Category | 抗原抗体 |
| Applications | WB |
| Reactivity | Human |
| Size | 100μg/50μg/20μg |
| Price | 2200.00/1200.00/560.00 |
| Gene_name | LRP6 |
| Protein_name | LRP6 (Ser1490) |
| Human swiss prot no | 4040 |
| Human swiss prot no | O75581 |
| Mouse gene id | 16974 |
| Mouse swiss prot no | O88572 |
| immunogen | Synthesized phosho peptide around human LRP6 (Ser1490) |
| Specificity | This antibody detects endogenous levels of Human LRP6 (phospho-Ser1490) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | Rabbit |
| Dilution | WB 1:1000-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage_stability | -20°C/1 year |
| othername | Low-density lipoprotein receptor-related protein 6 (LRP-6) |
| Observed_band | 177KD |
| Background | LDL receptor related protein 6(LRP6) Homo sapiens This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009], |
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