Catalog_no | AP1407 |
Product_name | Mre11 (phospho-Ser676) rabbit pAb |
Category | 抗原抗体 |
Applications | WB |
Reactivity | Human |
Size | 100μg/50μg/20μg |
Price | 2200.00/1200.00/560.00 |
Gene_name | MRE11A HNGS1 MRE11 |
Protein_name | Mre11 (Ser676) |
Human swiss prot no | 4361 |
Human swiss prot no | P49959 |
Mouse gene id | 17535 |
Mouse swiss prot no | Q61216 |
Rat gene id | 64046 |
Rat swiss prot no | Q9JIM0 |
immunogen | Synthesized phosho peptide around human Mre11 (Ser676) |
Specificity | This antibody detects endogenous levels of Human Mre11 (phospho-Ser676) |
Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Source | Rabbit |
Dilution | WB 1:1000-2000 |
Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
Concentration | 1 mg/ml |
Storage_stability | -20°C/1 year |
othername | Double-strand break repair protein MRE11A (Meiotic recombination 11 homolog 1) (MRE11 homolog 1) (Meiotic recombination 11 homolog A) (MRE11 homolog A) |
Observed_band | 80KD |
Background | MRE11 homolog, double strand break repair nuclease(MRE11) Homo sapiens This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008], |
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