| Catalog_no | AP1441 |
| Product_name | PKCα/β II (phospho-Thr638/641) rabbit pAb |
| Category | 抗原抗体 |
| Applications | WB |
| Reactivity | Human,Mouse |
| Size | 100μg/50μg/20μg |
| Price | 2200.00/1200.00/560.00 |
| Protein_name | PKCα/β II (Thr638/641) |
| Human swiss prot no | 5578 |
| Human swiss prot no | P17252 |
| Mouse gene id | 18750 |
| Mouse swiss prot no | P20444 |
| Rat swiss prot no | P05696 |
| immunogen | Synthesized phosho peptide around human PKCα (Thr638 and 641) |
| Specificity | This antibody detects endogenous levels of Human Mouse PKCα/β II (phospho-Thr638 or 641) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | Rabbit |
| Dilution | WB 1:1000-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage_stability | -20°C/1 year |
| othername | Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13) |
| Observed_band | 76KD |
| Background | protein kinase C alpha(PRKCA) Homo sapiens Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. [provided by RefSeq, Jul 2 |
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