| Catalog_no | AP1444 |
| Product_name | PKM2 (phospho-Tyr105) rabbit pAb |
| Category | 抗原抗体 |
| Applications | WB |
| Reactivity | Human,Mouse,Rat |
| Size | 100μg/50μg/20μg |
| Price | 2200.00/1200.00/560.00 |
| Gene_name | PKM OIP3 PK2 PK3 PKM2 |
| Protein_name | PKM2 (Tyr105) |
| Human swiss prot no | 5315 |
| Human swiss prot no | P14618 |
| Mouse gene id | 18746 |
| Mouse swiss prot no | P52480 |
| Rat gene id | 25630 |
| Rat swiss prot no | P11980 |
| immunogen | Synthesized phosho peptide around human PKM2 (Tyr105) |
| Specificity | This antibody detects endogenous levels of Human Mouse Rat PKM2 (phospho-Tyr105) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | Rabbit |
| Dilution | WB 1:1000-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage_stability | -20°C/1 year |
| othername | Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40) (Cytosolic thyroid hormone-binding protein) (CTHBP) (Opa-interacting protein 3) (OIP-3) (Pyruvate kinase 2/3) (Pyruvate kinase muscle isozyme) (Thyroid hormone-binding protein 1) (THBP1) (Tumor M2-PK) (p58) |
| Observed_band | 58KD |
| Background | pyruvate kinase, muscle(PKM) Homo sapiens This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011], |
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