| Catalog_no | AP1445 |
| Product_name | PLCγ1 (phospho-Ser1248) rabbit pAb |
| Category | 抗原抗体 |
| Applications | WB |
| Reactivity | Human,Mouse |
| Size | 100μg/50μg/20μg |
| Price | 2200.00/1200.00/560.00 |
| Gene_name | PLCG1 PLC1 |
| Protein_name | PLCγ1 (Ser1248) |
| Human swiss prot no | 5335 |
| Human swiss prot no | P19174 |
| Mouse gene id | 18803 |
| Mouse swiss prot no | Q62077 |
| Rat gene id | 25738 |
| Rat swiss prot no | P10686 |
| immunogen | Synthesized phosho peptide around human PLCγ1 (Ser1248) |
| Specificity | This antibody detects endogenous levels of Human Mouse PLCγ1 (phospho-Ser1248) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | Rabbit |
| Dilution | WB 1:1000-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage_stability | -20°C/1 year |
| othername | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (PLC-148) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-II) (PLC-II) (Phospholipase C-gamma-1) (PLC-gamma-1) |
| Observed_band | 150KD |
| Background | phospholipase C gamma 1(PLCG1) Homo sapiens The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
| Instructions | 
查看与下载 |
| Share |
Copyright © 2021 苏州博特龙免疫技术有限公司 版权所有 ，苏ICP备2021013855号-1
苏公网安备32050702011981号 
