| Catalog_no | AP1446 |
| Product_name | PLCγ2 (phospho-Tyr759) rabbit pAb |
| Category | 抗原抗体 |
| Applications | WB |
| Reactivity | Human,Mouse |
| Size | 100μg/50μg/20μg |
| Price | 2200.00/1200.00/560.00 |
| Gene_name | PLCG2 |
| Protein_name | PLCγ2 (Tyr759) |
| Human swiss prot no | 5336 |
| Human swiss prot no | P16885 |
| Mouse gene id | 234779 |
| Mouse swiss prot no | Q8CIH5 |
| Rat gene id | 29337 |
| Rat swiss prot no | P24135 |
| immunogen | Synthesized phosho peptide around human PLCγ2 (Tyr759) |
| Specificity | This antibody detects endogenous levels of Human Mouse PLCγ2 (phospho-Tyr759) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | Rabbit |
| Dilution | WB 1:1000-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage_stability | -20°C/1 year |
| othername | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-2) (Phospholipase C-IV) (PLC-IV) (Phospholipase C-gamma-2) (PLC-gamma-2) |
| Observed_band | 148KD |
| Background | phospholipase C gamma 2(PLCG2) Homo sapiens The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. [provided by RefSeq, Mar 2014], |
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